Cinnamic acids and derivatives
Pfaltz & Bauer 2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | 178.18 | 1 ML
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is for research use only.
- Purity: 99.94%
- Appearance: Solid, white to off-white
- Structure classification: Phenylpropanoids, Simple phenylpropanols
- Initial source: Plants (*Pulsatilla chinensis* (Bunge) Regel)
- Solubility (In Vitro): 100 mg/mL (561.23 mM) in DMSO (requires ultrasonication)
- Solubility (In Vivo): ≥ 2.5 mg/mL (14.03 mM) in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline (clear solution) or in 10% DMSO, 90% Corn Oil (clear solution)
Selleck Chemical LLC Ferulic acid methyl ester S5451-25mg
Ferulic acid methyl ester (Methyl Ferulate Methyl 4 -hydroxy-3 -methoxycinnamate) is a lipophilic derivative of ferulic acid which is a hydroxycinnamic acid that is abundant in plants It shows the strongest antioxidant activity and can protect against inflammation and cancer
Medchemexpress LLC Lassbio-1135 | 852453-71-5 | 99.1% | C18H14N4 | 10MG
LASSBio-1135 is an orally active TRPV1 antagonist and anti-inflammatory/analgesic research compound. It shows moderate inhibition of human PGHS-2 (IC50 = 18.5 μM) and has demonstrated in vivo efficacy reversing capsaicin-induced thermal hyperalgesia and reducing carrageenan-induced paw edema. The material is supplied as a white to off-white solid with reported high purity and recommended low-temperature storage for stability.
- orally active TRPV1 antagonist with anti-inflammatory and analgesic activity
- moderate inhibition of human PGHS-2 (IC50 = 18.5 μM)
- demonstrated in vivo efficacy in pain and inflammation models
- high purity solid, white to off-white appearance
- recommended storage at low temperatures for long-term stability
Apexbio Technology LLC Cinnamic acid 621-82-9 100mg
Cinnamic acid (CAS 621-82-9) is an aromatic unsaturated carboxylic acid naturally occurring in various plants particularly in cinnamon and vanilla It exhibits a range of bioactivities including antimicrobial anti-inflammatory and antioxidant effects Mechanistically cinnamic acid has been shown to modulate inflammatory pathways and oxidative stress responses thereby influencing cellular signaling cascades associated with disease progression Owing to these properties it is investigated in biomedical research for its potential in cancer intervention as well as for broader applications in pharmacological studies of inflammation and infection
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 500 MG
Cinnamic acid is a chemical compound with potential applications in cancer intervention. It has shown dose-dependent growth inhibition in various tumor cells, including glioblastoma, melanoma, prostate, and lung carcinoma cells, with IC50 values ranging from 1 to 4.5 mM.
- Potential use in cancer intervention.
- Exhibits dose-dependent growth inhibition in tumor cells.
- Induces morphological changes consistent with melanocyte differentiation.
- Causes a dose-dependent loss of invasive capacity in treated tumor lines.
- Effective in glioblastoma, melanoma, prostate, and lung carcinoma cells.
Medchemexpress LLC 3,4,5-Trimethoxycinnamic acid | 90-50-6 | 99.96% | 238.24 | 1 ML
3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of *Polygala tenuifolia WILLD*. It exhibits an anti-stress effect and prolongs sleeping time in animals. This compound increases the expression of GAD65 and the γ-subunit of the GABAA receptor, but does not affect the amounts of α- or β-subunits. It is for research use only.
- Anti-stress effect
- Prolongs sleeping time in animals
- Increases expression of GAD65 and γ-subunit of GABAA receptor
- For research use only
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | MFCD00017208 | 99.9% | 208.21 g/mol | C11H12O4 | 10 G
Ferulic acid methyl ester is the methyl ester derivative of ferulic acid used as a research reagent. It shows antioxidant and anti-inflammatory properties, is reported to inhibit p38 MAPK and modulate autophagy, and is suitable for biochemical and cell-based studies; batch-specific purity and safety documentation are available from the manufacturer.
- Methyl ester derivative of ferulic acid with antioxidant activity.
- Reported inhibitor of p38 MAPK and modulator of autophagy pathways.
- Cell membrane and brain permeable, suitable for cell-based assays.
- High batch-specific purity with certificate of analysis and SDS documentation available.
- Available in multiple pack sizes for research use, including a 10 g pack.
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | CB1140462 | 99.9% | 164.16 | 5 G
2-Hydroxycinnamic acid is a phenolic acid possessing antimicrobial and antioxidant properties. It exhibits antimicrobial activity against Staphylococcus aureus and has shown to not be susceptible to drug resistance. Additionally, 2-Hydroxycinnamic acid demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus, with an IC50 of 0.3 mM. It also has neuroprotective and antitumor activities.
- Possesses antimicrobial properties.
- Has antioxidant properties.
- Exhibits antimicrobial activity against Staphylococcus aureus.
- Not susceptible to drug resistance.
- Demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus.
- Has neuroprotective activities.
- Has antitumor activities.
Medchemexpress LLC 4-nitrocinnamic acid | 619-89-6 | MFCD00007381 | 99.9% | 193.16 g/mol | C9H7NO4 | 25 G
4-Nitrocinnamic acid is a nitro-substituted cinnamic acid used as a research reagent and synthetic building block. It is applied in organic synthesis and materials research and is supplied with analytical characterization to support laboratory use.
- High purity for reliable experimental results.
- Suitable as a building block in organic synthesis.
- Soluble in common organic solvents for easy handling.
- Characterized by CAS 619-89-6 and molecular formula C9H7NO4.
- Supplied in controlled pack sizes for laboratory use.
eMolecules 32862-97-8 | 3-Bromocinnamic acid | Oakwood Chemicals227.057 | C9H7BrO2 | 98.000 | OC(=O)\C=C\c1cccc(Br)c1 | 1g | 480099101
3-Bromocinnamic acid | Oakwood Chemicals | 32862-97-8227.057 | C9H7BrO2 | 98.000 | OC(=O)\C=C\c1cccc(Br)c1 | 1g | 480099101
Apexbio Technology LLC Ozagrel 82571-53-7 10mg
Ozagrel (CAS 82571-53-7) is a selective inhibitor of thromboxane A synthase an enzyme involved in the conversion of prostaglandin H to thromboxane A a potent mediator of platelet aggregation and vasoconstriction Ozagrel demonstrates high inhibitory potency with an IC of 4 nM indicating strong activity at low concentrations This compound is widely utilized in research to investigate thromboxane-dependent signaling pathways vascular biology and platelet function as well as in studies exploring potential therapeutic interventions targeting thrombotic and cardiovascular disorders
Cayman Chemical m-Coumaric Acid, Purity: ≥98%, CAS: 588-30-7, 1 g
An active metabolite of polyphenols; inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM); induces neurite outgrowth of fetal rat hippocampal neurons at 10 µM; induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cells at 5 and 10 mM, respectively; increases locomotor activity in mice at 3 mmol/kg
Apexbio Technology LLC BIBF 1202 894783-71-2 10mg
BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research