Cinnamic acids and derivatives
eMolecules 2'-(3-Fluorobenzyloxy)acetophenone | 845823-26-9 | MFCD06411645 | 1g
Oakwood Chemical | 2'-(3-Fluorobenzyloxy)acetophenone | 1g | 537680623 | 023221 | | 845823-26-9 | MFCD06411645 | 244.265 | C15H13FO2
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Medchemexpress LLC Entacapone | 130929-57-6 | 99.97% | C14H15N3O5 | 50 MG
Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It is selective for COMT over other catecholamine metabolizing enzymes and can be used for Parkinson's disease research. Entacapone also inhibits FTO demethylation, making it relevant for metabolic disorders research.
- Inhibits COMT with IC50 values in the nanomolar range
- Demonstrates agonist activity at GPR35 in HT-29 and U2OS cells
- Enhances m6A on mRNA in Hep-G2 cells
- Decreases body weight and fat mass in obese mouse models
- Reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides
Sigma Aldrich Fine Chemicals Biosciences α-Cyano-4-hydroxycinnamic acid, 28166-41-8, MFCD00004204, 10x10mg
Molecular Formula: HOC6H4CH=C(CN)CO2H, Molecular Weight: 189.17, Beilstein Registry Number: 3271427
Cayman Chemical Plnt TurmerIc CurcumIn 5g
A yellow pigment with diverse biological activities; inhibits NO production (IC50 = 6 μM) and reduces iNOS activity in LPS-stimulated RAW 264.7 cells; inhibits release of histamine and the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 from HMC-1 mast cells; decreases serum levels of histamine and TNF-α, inhibits histopathological changes of nasal mucosa, and decreases the number of sneezes and nasal rubbing in a mouse model of ovalbumin-induced rhinitis; prevents ovalbumin-induced accumulation of 3-NT in mouse heart; reduces TPA-induced tumor formation in mouse skin (1-10 μmol); reduces the number of tongue neoplasms and preneoplastic lesions induced by 4-NQO in rats
eMolecules Ambeed / 2-Methoxycinnamic Acid / 5g / 490558558 / A377987 / / 6099-03-2 / MFCD00064238 / 178.187 / C10H10O3
Ambeed / 2-Methoxycinnamic Acid / 5g / 490558558 / A377987 / / 6099-03-2 / MFCD00064238 / 178.187 / C10H10O3
Cayman Chemical m-CoumarIc AcId 10g
An active metabolite of polyphenols; inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM); induces neurite outgrowth of fetal rat hippocampal neurons at 10 µM; induces apoptosis and cell cycle arrest at the G0/G1 phase in HeLa cells at 5 and 10 mM, respectively; increases locomotor activity in mice at 3 mmol/kg
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3894150 ALPHA CYANO 4 HYDROXYCINNAMIC
Sigma Aldrich Fine Chemicals Biosciences alpha-Cyano-4-hydroxycinnamic acid >=98% (TLC), powder | 28166-41-8 | MFCD00004204 | 25G
alpha-Cyano-4-hydroxycinnamic acid >=98% (TLC), powder | Purity: >=98% (TLC) | Mol Wt: 189.17 | 28166-41-8 | MFCD00004204 | 25G
Cayman Chemical p-CoumarIc AcId 100g
A hydroxy derivative of cinnamic acid that can be found in a variety of edible plants that is reported to have antioxidant, anti-inflammatory, and antimicrobial activity
Apexbio Technology LLC Tyrphostin AG 1296 146535-11-7 10mM (in 1mL DMSO)
Tyrphostin AG 1296 (CAS 146535-11-7) is a selective inhibitor of platelet-derived growth factor receptor (PDGFR) kinase via ATP-competitive binding Its inhibitory activity (IC50 0 3 0 5 M) results from inducing conformational changes in the ATP-binding domain of PDGFR blocking receptor autophosphorylation induced by ligand binding In vitro studies demonstrate inhibition of PDGF-stimulated mitogenesis (IC50 1 5 M) and cell proliferation (IC50 3 2 M) using Swiss 3T3 cells without significant effects on EGF receptor signaling at concentrations up to 100 M Tyrphostin AG 1296 serves as a research tool for investigating PDGFR-mediated signaling pathways
Medchemexpress LLC cis-Ferulic acid 4-O-β-D-glucopyranoside | 94942-20-8 | 356.32 | 5 MG
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica. This compound exhibits antioxidant activity and a potent inhibitory effect on Phosphatase PTP1B.
- Exhibits antioxidant activity.
- Potent inhibitory effect on Phosphatase PTP1B.
Medchemexpress LLC Tyrphostin AG 879 | 148741-30-4 | MFCD00236450 | 99.3% | 10 MG
Tyrphostin AG 879 is a small-molecule tyrosine kinase inhibitor widely used in laboratory research. It shows selectivity for ErbB2 (HER2) with a reported IC50 of about 1 μM and reduces TrkA phosphorylation at higher micromolar concentrations. The compound is supplied as a powder, is soluble in DMSO, and is intended for in vitro signaling and kinase pathway studies.
Cambridge Isotope Laboratories 4-HYDROXY-3-METHOXYCINNAMIC ACID (FERULIC ACID) (1',2',3'-13C3, 99%), 1 MG, 1261170-81-3
4-HYDROXY-3-METHOXYCINNAMIC ACID (FERULIC ACID) (1',2',3'-13C3, 99%), 1 MG, 1261170-81-3